IRRODL Volume 4, Number 1

Basic and Clinical Neuroscience, Volume 4, Number 4, Full Text

1874 - 2718 , Volume 4 , Number 1

The UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase LpxC catalyzes the committed reaction of lipid A biosynthesis, an essential pathway in Gram-negative bacteria. We report the backbone resonance assignments of the 34 kDa LpxC from Escherichia coli in complex with the antibiotic L-161,240 using multidimensional, multinuclear NMR experiments. The H chemical shifts of complexed L-1...

Basic and Clinical Neuroscience, Volume 4, Number 2, Full Text

Abstracts Volume 4 Number 4

The vibration phenomenon represents the cause of many problems in metal cutting processes. It has a big influence on the quality of the machining operation, tool life and machine precision. Drilling operation is a common metal cutting process where quality of the hole form is often a critical issue. Therefore, it was necessary to predict these vibrations. The first part of this paper deals with...

Abstracts Volume 4 Number 4

The simulation of the process planning is a decisive stage in the manufacturing process of a set of parts. This simulation is generally carried out by the calculation of the working dimensions (WD) according to the blueprint dimensions (BPD), to the means of production and to the machining process. The calculation and the generating of the working dimensions can be done by using different metho...